Sodium Chloride Injectable USP

White crystalline powder

White or almost white, crystalline powder or colorless crystals or white or almost white pearls.

Solubility

Freely soluble in water, practically insoluble in anhydrous ethanol.

Freely soluble in water, practically insoluble in anhydrous ethanol.

Identification

Complies

(A)(B)Gives the reaction of sodium

Appearance of solution

Solution S is clear and colorless

Solution S is clear and colorless

Acidity or Alkalinity

2.0 ml is required

NMT 0.5 ml of 0.01M Hydrochloric acid or 0.01M sodium hydroxide is required

Bromides

Complies

NMT 100PPM

Ferro cyanide

Complies

No blue color develops within 10 minutes

Iodides

Complies

The mixture shows no blue color

Nitrites

Complies

NLT 0.01 PPM Absorbance at 354 nm.

Phosphates

Complies

NMT 25 PPM

Sulphate

Complies

NMT 200 PPM

Arsenic

Complies

NMT 1 PPM

Barium

Complies

As per USP

Iron

Complies

NMT 2 PPM

Magnesium and alkaline-earth metals

Complies

NMT 100 PPM

Potassium

Complies

NMT 500 PPM

Loss on Drying

0.40%

NMT 0.5% W/W

Assay

99.77% ODB

99.0% TO 100.5% ODB

MICROBIAL LIMIT

Bacterial Endotoxins test

Complies

NMT 5 IU/g

Microbial count

Complies

TAMC NMT 100 CFU/g
TYMC NMT 10 CFU/g